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Models Of Seizures And Epilepsy

Models Of Seizures And Epilepsy
Author: Asla Pitkänen
Publisher: Academic Press
ISBN: 012804067X
Size: 46.25 MB
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Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Models of Seizures and Epilepsy
Language: en
Pages: 1178
Authors: Asla Pitkänen, Paul Buckmaster, DVM, PhD, Aristea S Galanopoulou, Solomon L. Moshé
Categories: Science
Type: BOOK - Published: 2017-06-14 - Publisher: Academic Press
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in
Animal Models of Epilepsy
Language: en
Pages: 272
Authors: Scott C. Baraban
Categories: Epilepsy
Type: BOOK - Published: 2009-01-01 - Publisher:
Animal models provide a means to investigate fundamental mechanisms of abnormal electrical discharge i.e., seizures. Taking advantage of transgenic and homologous recombination techniques, laboratories have recently moved beyond the standard convulsant or stimulation models in rat to develop novel mouse models of epilepsy. This book provides a review of the
Experimental Models of Epilepsy and Related Comorbidities
Language: en
Pages:
Authors: Mohd. Farooq Shaikh, Ayanabha Chakraborti, Annamaria Vezzani, Jafri Malin Abdullah
Categories: Epilepsy
Type: BOOK - Published: 2019-06-19 - Publisher: Frontiers Media SA
Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational
Neuropharmacology Methods in Epilepsy Research
Language: en
Pages: 272
Authors: Steven L. Peterson, Timothy E. Albertson
Categories: Medical
Type: BOOK - Published: 2019-05-07 - Publisher: CRC Press
There is an estimated 2.5 million epileptics in the US and perhaps some 40 million worldwide. As research has become increasingly molecular in scope, fewer scientists are trained in the US on basic, integrated epilepsy techniques. One frustration in neuroscience today is the application of state-of-the-art molecular biology techniques to
Behavioral Aspects of Epilepsy
Language: en
Pages: 264
Authors: Gregory L. Holmes, MD, Steven C. Schachter, Dr. Dorothee GA Kasteleijn-Nolst Trenite, "MD,MPH"
Categories: Medical
Type: BOOK - Published: 2007-10-15 - Publisher: Demos Medical Publishing
The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. Behavioral Aspects of Epilepsy: Principles and Practice is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers
Astrocytes and Epilepsy
Language: en
Pages: 394
Authors: Jacqueline A. Hubbard, Devin K. Binder
Categories: Medical
Type: BOOK - Published: 2016-07-05 - Publisher: Academic Press
Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory".
Encyclopedia of Basic Epilepsy Research
Language: en
Pages: 1832
Authors: Jacqueline A. Hubbard, Devin K. Binder
Categories: Medical
Type: BOOK - Published: 2009-05-27 - Publisher: Academic Press
As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of
Epileptic Seizures and the EEG
Language: en
Pages: 370
Authors: Andrea Varsavsky, Iven Mareels, Mark Cook
Categories: Medical
Type: BOOK - Published: 2016-04-19 - Publisher: CRC Press
A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering
Bundle for Epilepsy Researchers
Language: en
Pages:
Authors: Ruben Kuzniecky, Asla Pitknen, Ivan Soltesz
Categories: Medical
Type: BOOK - Published: 2008-10-03 - Publisher: Academic Press
Combining three essential Academic Press books, this bundle provides reference information for epilepsy researchers at a great price. Magnetic Resonance in Epilepsy is an in-depth look at the advances in imaging techology as applied to epilepsy research. Models of Seizures and Epilepsy speaks to the needs of both basic neuroscientists
Models of Seizures and Epilepsy
Language: en
Pages: 712
Authors: Asla Pitkänen, Philip A. Schwartzkroin, Solomon L. Moshé
Categories: Medical
Type: BOOK - Published: 2005-10-04 - Publisher: Elsevier
An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30